This study investigated the impact of cultural dimensions (included power distance, uncertainty avoidance, collectivism/ individualism, masculinity/femininity, long term orientation and indulgence/restraint) on job satisfaction between non managerial Thai and Vietnamese employees who work in the private business sector. 460 questionnaires were distributed by hand and online in the three biggest cities (Ho Chi Minh, Hanoi, and Danang) in Vietnam and Bangkok Metropolitan region in Thai land. Multiple linear regressions, independent sample T test, and ANOVA were applied for data analysis. The results showed that there is a significant relationship between cultural dimension and job satisfaction (intrinsic/extrinsic). The impact of cultural dimension on job satisfaction of non managerial Vietnamese employees is stronger than on job satisfaction of non managerial Thai employees. In addition, there is no significant difference in job satisfaction between non managerial Thai and Vietnamese employees. There is no significant difference in job satisfaction between non managerial Thai and Vietnamese employees reflected by gender, no significant difference in job satisfaction of Thai and Vietnamese employees among income groups. And there is a significant difference in job satisfaction of non managerial Vietnamese employees among education groups and there is no significant difference in job satisfaction of non managerial Thai employees among education groups. Based on these results, the researcher provides some recommendations for managers in both countries.