Heating a mixture of pyridine, redistilled acetophenone and iodine yielded N-acetophenone pyridinium iodide (I) in excellent yield. Reaction of (I) with diazonium salts (II) in absolute ethanol afforded tetrazines (III) in the yields ranging from 35 to 45%. The target candidate molecules (III) were screened for their antiparkinsonism activity against oxotremorine induced tremor in albino mice of either sex.