The field experiment on wheat was conducted at pot culture house of the Department of Soil Science and Agril. Chemistry, C.S. Azad University of Agriculture and Technology, Kanpur during rabi season 2012-13. The doses of experiment were T-1 (Control), T-2 120 kg N + 60 Kg P + 60 Kg Kha-1, T-3 120 kg N + 60 Kg P + 60 Kg Kha-1 + vermicompost, (5 q ha-1), T-4 120 kg N + 60 Kg P + 60 Kg K ha-1 Azotobacter, T-5 120 kg N + 60 Kg K ha-1 + 60 K + 10 Kg Zn, T-6 120 kg N + 60 Kg P + 60 Kg K ha + vermicompost (5 q ha-1) + Azotobacter and T-7 120 kg N + 60 Kg P + 60 Kg K + Vermicompost 5 q ha-1 + Azotobacter + 10 kg Zn. The result showed that the grain yield of wheat varied from 30.00 to 53.00 q ha-1 and straw yield of wheat from 40.00 to 67.00 q ha-1. It was noted the N uptake varied from 70.80 to 145.64 kg ha 1, P from 13.60 to 31.78 kg ha-1, K from 74.20 to 148.59 kg ha-1 and Zinc from 84.00 to 250.45 g ha-1. The lysine content in wheat varied from 3.0 to 2.84 per cent and protein content in wheat varied from 11.25 to 12.75 per cent. The dose of N120 + P60 + K60 + Vermicompost 5 q ha-1 + Azotobacter + Zn10 were found most suitable in respect of crop yield, uptake of nutrient and quality of wheat.